Polynucleotide 5'-phosphatase
- Polynucleotide 5'-phosphatase
In enzymology, a polynucleotide 5'-phosphatase (EC number|3.1.3.33) is an enzyme that catalyzes the chemical reaction
:a 5'-phosphopolynucleotide + H2O a polynucleotide + phosphate
Thus, the two substrates of this enzyme are 5'-phosphopolynucleotide and H2O, whereas its two products are polynucleotide and phosphate.
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is polynucleotide 5'-phosphohydrolase. This enzyme is also called 5'-polynucleotidase.
tructural studies
As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1D8H, PDB link|1D8I, PDB link|1I9S, PDB link|1I9T, and PDB link|1YN9.
References
*
External links
::"The CAS registry number for this enzyme class is CAS registry|37288-17-8."
Gene Ontology (GO) codes
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