Phosphatidylinositol deacylase

Phosphatidylinositol deacylase

In enzymology, a phosphatidylinositol deacylase (EC number|3.1.1.52) is an enzyme that catalyzes the chemical reaction

:1-phosphatidyl-D-myo-inositol + H2O ightleftharpoons 1-acylglycerophosphoinositol + a carboxylate

Thus, the two substrates of this enzyme are 1-phosphatidyl-D-myo-inositol and H2O, whereas its two products are 1-acylglycerophosphoinositol and carboxylate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 1-phosphatidyl-D-myo-inositol 2-acylhydrolase. Other names in common use include phosphatidylinositol phospholipase A2, and phospholipase A2.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|81604-94-6."

Gene Ontology (GO) codes


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  • phosphatidylinositol deacylase — phos·pha·ti·dyl·ino·si·tol de·acyl·ase (fos″fə tiґdəl ĭ noґsĭ tol de aґsəl ās) [EC 3.1.1.52] formal EC nomenclature for a phospholipase A2 specific for phosphatidylinositol. See phospholipase A2 …   Medical dictionary

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • phospholipase A2 — [EC 3.1.1.4] any esterase that catalyzes the hydrolysis of the central acyl group from a membrane phospholipid, generating a free fatty acid and a lysophospholipid; this reaction is important in the digestion of dietary phospholipids, and it… …   Medical dictionary

  • metabolism — /meuh tab euh liz euhm/, n. 1. Biol., Physiol. the sum of the physical and chemical processes in an organism by which its material substance is produced, maintained, and destroyed, and by which energy is made available. Cf. anabolism, catabolism …   Universalium

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