N-acylneuraminate-9-phosphatase

N-acylneuraminate-9-phosphatase
N-acylneuraminate-9-phosphatase
Identifiers
EC number 3.1.3.29
CAS number 37288-13-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a N-acylneuraminate-9-phosphatase (EC 3.1.3.29) is an enzyme that catalyzes the chemical reaction

N-acylneuraminate 9-phosphate + H2O \rightleftharpoons N-acylneuraminate + phosphate

Thus, the two substrates of this enzyme are N-acylneuraminate 9-phosphate and H2O, whereas its two products are N-acylneuraminate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is N-acylneuraminate-9-phosphate phosphohydrolase. Other names in common use include acylneuraminate 9-phosphatase, N-acylneuraminic acid 9-phosphate phosphatase, and N-acylneuraminic (sialic) acid 9-phosphatase. This enzyme participates in aminosugars metabolism.

References

  • Jourdian GW, Swanson A, Watson D and Roseman S (1966). "N-Acetylneuraminic (sialic) acid 9-phosphatase". Methods Enzymol. 8: 205–208.