Hydroxymethylglutaryl-CoA hydrolase

Hydroxymethylglutaryl-CoA hydrolase

In enzymology, a hydroxymethylglutaryl-CoA hydrolase (EC number| is an enzyme that catalyzes the chemical reaction

:(S)-3-hydroxy-3-methylglutaryl-CoA + H2O ightleftharpoons CoA + 3-hydroxy-3-methylglutarate

Thus, the two substrates of this enzyme are (S)-3-hydroxy-3-methylglutaryl-CoA and H2O, whereas its two products are CoA and 3-hydroxy-3-methylglutarate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is (S)-3-hydroxy-3-methylglutaryl-CoA hydrolase. Other names in common use include beta-hydroxy-beta-methylglutaryl coenzyme A hydrolase, beta-hydroxy-beta-methylglutaryl coenzyme A deacylase, hydroxymethylglutaryl coenzyme A hydrolase, hydroxymethylglutaryl coenzyme A deacylase, and 3-hydroxy-3-methylglutaryl-CoA hydrolase.



External links

::"The CAS registry number for this enzyme class is CAS registry|9025-89-2."

Gene Ontology (GO) codes

Wikimedia Foundation. 2010.

Игры ⚽ Нужно сделать НИР?

Look at other dictionaries:

  • (hydroxymethylglutaryl-CoA reductase (NADPH))-phosphatase — In enzymology, a [hydroxymethylglutaryl CoA reductase (NADPH)] phosphatase (EC number| is an enzyme that catalyzes the chemical reaction: [hydroxymethylglutaryl CoA reductase (NADPH)] phosphate + H2O ightleftharpoons… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

  • CHOLESTÉROL — Le cholestérol est une biomolécule très répandue chez la plupart des organismes animaux, mais absente des végétaux et des micro organismes. Le cholestérol est un solide blanc, cristallin, insoluble dans l’eau, soluble dans les liquides organiques …   Encyclopédie Universelle

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”