Fructose-2,6-bisphosphate 2-phosphatase

Fructose-2,6-bisphosphate 2-phosphatase

In enzymology, a fructose-2,6-bisphosphate 2-phosphatase (EC number|3.1.3.46) is an enzyme that catalyzes the chemical reaction

:beta-D-fructose 2,6-bisphosphate + H2O ightleftharpoons D-fructose 6-phosphate + phosphate

Thus, the two substrates of this enzyme are beta-D-fructose 2,6-bisphosphate and H2O, whereas its two products are D-fructose 6-phosphate and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is beta-D-fructose-2,6-bisphosphate 2-phosphohydrolase. Other names in common use include fructose-2,6-bisphosphatase, and D-fructose-2,6-bisphosphate 2-phosphohydrolase. This enzyme participates in fructose and mannose metabolism.

tructural studies

As of late 2007, 13 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1BIF, PDB link|1C7Z, PDB link|1C80, PDB link|1C81, PDB link|1FBT, PDB link|1K6M, PDB link|1TIP, PDB link|2AXN, PDB link|2BIF, PDB link|2DWO, PDB link|2DWP, PDB link|2I1V, and PDB link|3BIF.

References

*

External links

::"The CAS registry number for this enzyme class is CAS registry|81611-75-8."

Gene Ontology (GO) codes


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