Deoxynucleotide 3'-phosphatase

Deoxynucleotide 3'-phosphatase
deoxynucleotide 3'-phosphatase
Identifiers
EC number 3.1.3.34
CAS number 37288-18-9
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a deoxynucleotide 3'-phosphatase (EC 3.1.3.34) is an enzyme that catalyzes the chemical reaction

a deoxynucleoside 3'-phosphate + H2O \rightleftharpoons a deoxynucleoside + phosphate

Thus, the two substrates of this enzyme are deoxynucleoside 3'-phosphate and H2O, whereas its two products are deoxynucleoside and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is deoxyribonucleotide 3'-phosphohydrolase. Other names in common use include 3'-deoxynucleotidase, and 3'-deoxyribonucleotidase.

References

  • Becker A, Hurwitz J (1967). "The enzymatic cleavage of phosphate termini from polynucleotides". J. Biol. Chem. 242 (5): 936–50. PMID 4289819.