(acyl-carrier-protein) phosphodiesterase

(acyl-carrier-protein) phosphodiesterase

In enzymology, a [acyl-carrier-protein] phosphodiesterase (EC number|3.1.4.14) is an enzyme that catalyzes the chemical reaction

:holo- [acyl-carrier-protein] + H2O ightleftharpoons 4'-phosphopantetheine + apo- [acyl-carrier-protein]

Thus, the two substrates of this enzyme are [holo- [acyl-carrier-protein] and H2O, whereas its two products are 4'-phosphopantetheine and [apo- [acyl-carrier-protein] .

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is holo- [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase. Other names in common use include ACP hydrolyase, ACP phosphodiesterase, AcpH, and [acyl-carrier-protein] 4'-pantetheine-phosphohydrolase. This enzyme participates in pantothenate and coa biosynthesis.

tructural studies

As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1T5B and PDB link|1TIK.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|37288-21-4."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужно решить контрольную?

Look at other dictionaries:

  • Protein — A large molecule composed of one or more chains of amino acids in a specific order determined by the base sequence of nucleotides in the DNA coding for the protein. Proteins are required for the structure, function, and regulation of the body s… …   Medical dictionary

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Medizinische Abkürzungen — Dies ist eine Liste der Abkürzungen und Akronyme, die in der klinischen Medizin verwendet werden. Anatomische Akronyme werden von den Lemmata Nomenklatur (Anatomie) sowie Lage und Richtungsbezeichnungen abgedeckt. weitere Links zu medizinischen… …   Deutsch Wikipedia

  • Metabolism — Cell metabolism redirects here. For the journal, see Cell Metabolism. Structure of adenosine triphosphate, a central intermediate in energy metabolism Metabolism (from Greek: μεταβολή metabolē , change or Greek: μεταβολισμός metabolismos,… …   Wikipedia

  • Aspirin — Asprin redirects here. For the author, see Robert Asprin. Aspirin …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”