2-pyrone-4,6-dicarboxylate lactonase

2-pyrone-4,6-dicarboxylate lactonase

In enzymology, a 2-pyrone-4,6-dicarboxylate lactonase (EC number|3.1.1.57) is an enzyme that catalyzes the chemical reaction

:2-pyrone-4,6-dicarboxylate + H2O ightleftharpoons 4-carboxy-2-hydroxyhexa-2,4-dienedioate

Thus, the two substrates of this enzyme are 2-pyrone-4,6-dicarboxylate and H2O, whereas its product is 4-carboxy-2-hydroxyhexa-2,4-dienedioate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 2-pyrone-4,6-dicarboxylate lactonohydrolase. This enzyme participates in benzoate degradation via hydroxylation.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2QAH.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|84177-55-9."

Gene Ontology (GO) codes


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