2-pyrone-4,6-dicarboxylate lactonase

2-pyrone-4,6-dicarboxylate lactonase

In enzymology, a 2-pyrone-4,6-dicarboxylate lactonase (EC number|3.1.1.57) is an enzyme that catalyzes the chemical reaction

:2-pyrone-4,6-dicarboxylate + H2O ightleftharpoons 4-carboxy-2-hydroxyhexa-2,4-dienedioate

Thus, the two substrates of this enzyme are 2-pyrone-4,6-dicarboxylate and H2O, whereas its product is 4-carboxy-2-hydroxyhexa-2,4-dienedioate.

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is 2-pyrone-4,6-dicarboxylate lactonohydrolase. This enzyme participates in benzoate degradation via hydroxylation.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|2QAH.

References

*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|84177-55-9."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Поможем сделать НИР

Look at other dictionaries:

  • List of EC numbers (EC 3) — This list contains a list of EC numbers for the third group, EC 3, hydrolases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 3.1: Acting on Ester BondsEC… …   Wikipedia

  • Hydrolase — Cristal de lysozyme Les hydrolases constituent une classe d enzymes qui catalysent les réactions d hydrolyse de molécules suivant la réaction générale : R R + H2O ⇌ R OH + R H On y trouve par exemple les estérases, qui hydrolysent les …   Wikipédia en Français

  • EC 3.1 — Le groupe EC3.1 est un groupe d hydrolases rassemblant les estérases, c est à dire les enzymes catalysant la réaction générale : R O R + H2O ⇌ R OH + R OH où R représente un acide quelconque et R son substrat. En fonction du milieu, l ester… …   Wikipédia en Français

Share the article and excerpts

Direct link
… Do a right-click on the link above
and select “Copy Link”