UDP-sugar diphosphatase

In enzymology, an UDP-sugar diphosphatase (EC number|3.6.1.45) is an enzyme that catalyzes the chemical reaction

:UDP-sugar + H₂O $ightleftharpoons$ UMP + alpha-D-aldose 1-phosphate

Thus, the two substrates of this enzyme are UDP-sugar and H₂O, whereas its two products are UMP and alpha-D-aldose 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in phosphorus-containing anhydrides. The systematic name of this enzyme class is UDP-sugar sugarphosphohydrolase. Other names in common use include nucleosidediphosphate-sugar pyrophosphatase, nucleosidediphosphate-sugar diphosphatase, UDP-sugar hydrolase, and UDP-sugar pyrophosphatase.

tructural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1HO5, PDB link|1HP1, PDB link|1HPU, PDB link|1OI8, PDB link|1OID, and PDB link|1OIE.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|57127-20-5."

Gene Ontology (GO) codes