- Na+-exporting ATPase
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sodium-exporting ATPase, phosphorylative mechanism Identifiers EC number 3.6.3.7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a Na+-exporting ATPase (EC 3.6.3.7) is an enzyme that catalyzes the chemical reaction
- ATP + H2O + Na+in ADP + phosphate + Na+out
The 3 substrates of this enzyme are ATP, H2O, and Na+, whereas its 3 products are ADP, phosphate, and Na+.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Na+-exporting).
References
- Wieland J, Nitsche AM, Strayle J, Steiner H, Rudolph HK (1995). "The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane". EMBO J. 14 (16): 3870–82. PMC 394466. PMID 7664728. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=394466.
- Catty P, de Kerchove d'Exaerde A, Goffeau A (1997). "The complete inventory of the yeast Saccharomyces cerevisiae P-type transport ATPases". FEBS. Lett. 409 (3): 325–32. doi:10.1016/S0014-5793(97)00446-8. PMID 9224683.
- Cheng J, Guffanti AA, Krulwich TA (1997). "A two-gene ABC-type transport system that extrudes Na+ in Bacillus subtilis is induced by ethanol or protonophore". Mol. Microbiol. 23 (6): 1107–20. doi:10.1046/j.1365-2958.1997.2951656.x. PMID 9106203.
- Saier MH Jr (1998). "Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya". Adv. Microb. Physiol. 40: 81–136. doi:10.1016/S0065-2911(08)60130-7. PMID 9889977.
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