Asparaginyl-tRNA synthase (glutamine-hydrolysing)

In enzymology, an asparaginyl-tRNA synthase (glutamine-hydrolysing) (EC number|6.3.5.6) is an enzyme that catalyzes the chemical reaction

:ATP + aspartyl-tRNAAsn + L-glutamine $$ightleftharpoons ADP + phosphate + asparaginyl-tRNAAsn + L-glutamate

The 3 substrates of this enzyme are ATP, aspartyl-tRNA(Asn), and L-glutamine, whereas its 4 products are ADP, phosphate, asparaginyl-tRNA(Asn), and L-glutamate.

This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. The systematic name of this enzyme class is aspartyl-tRNAAsn:L-glutamine amido-ligase (ADP-forming). Other names in common use include Asp-AdT, Asp-tRNAAsn amidotransferase, aspartyl-tRNAAsn amidotransferase, and Asn-tRNAAsn:L-glutamine amido-ligase (ADP-forming). This enzyme participates in glutamate metabolism and alanine and aspartate metabolism.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|37211-76-0."

Gene Ontology (GO) codes