Tyrosine phenol-lyase

In enzymology, a tyrosine phenol-lyase (EC number|4.1.99.2) is an enzyme that catalyzes the chemical reaction

:L-tyrosine + H₂O $ightleftharpoons$ phenol + pyruvate + NH₃

Thus, the two substrates of this enzyme are L-tyrosine and H₂O, whereas its 3 products are phenol, pyruvate, and NH₃.

This enzyme belongs to the family of lyases, specifically in the "catch-all" class of carbon-carbon lyases. The systematic name of this enzyme class is L-tyrosine phenol-lyase (deaminating; pyruvate-forming). Other names in common use include beta-tyrosinase, and L-tyrosine phenol-lyase (deaminating). This enzyme participates in tyrosine metabolism and nitrogen metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1C7G, PDB link|1TPL, PDB link|2EZ1, PDB link|2EZ2, and PDB link|2TPL.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9059-31-8."

Gene Ontology (GO) codes