Phosphatidylserine decarboxylase

In enzymology, a phosphatidylserine decarboxylase (EC number|4.1.1.65) is an enzyme that catalyzes the chemical reaction

:phosphatidyl-L-serine $ightleftharpoons$ phosphatidylethanolamine + CO₂

Hence, this enzyme has one substrate, phosphatidyl-L-serine, and two products, phosphatidylethanolamine and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is phosphatidyl-L-serine carboxy-lyase (phosphatidylethanolamine-forming). Other names in common use include PS decarboxylase, and phosphatidyl-L-serine carboxy-lyase. This enzyme participates in glycine, serine and threonine metabolism and glycerophospholipid metabolism. It has 2 cofactors: pyridoxal phosphate, and Pyruvate.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9054-78-8."

Gene Ontology (GO) codes