L-fuculose-phosphate aldolase

In enzymology, a L-fuculose-phosphate aldolase (EC number|4.1.2.17) is an enzyme that catalyzes the chemical reaction

: L-fuculose-1-phosphate $ightleftharpoons$ glycerone phosphate + ("S")-lactaldehyde

Hence, this enzyme has one substrate, L-fuculose-1-phosphate, and two products, glycerone phosphate and (S)-lactaldehyde.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-fuculose-1-phosphate (S)-lactaldehyde-lyase (glycerone-phosphate-forming). Other names in common use include L-fuculose 1-phosphate aldolase, fuculose aldolase, and L-fuculose-1-phosphate lactaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.

tructural studies

As of late 2007, 20 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1DZU, PDB link|1DZV, PDB link|1DZW, PDB link|1DZX, PDB link|1DZY, PDB link|1DZZ, PDB link|1E46, PDB link|1E47, PDB link|1E48, PDB link|1E49, PDB link|1E4A, PDB link|1E4B, PDB link|1E4C, PDB link|1FUA, PDB link|2FK5, PDB link|2FLF, PDB link|2FUA, PDB link|2OPI, PDB link|3FUA, and PDB link|4FUA.

See also

* Fuculose
* L-Fuculose kinase (abbreviated "FucK")

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9024-54-8."

Gene Ontology (GO) codes