Arginine decarboxylase

In enzymology, an arginine decarboxylase (EC number|4.1.1.19) is an enzyme that catalyzes the chemical reaction

:L-arginine $ightleftharpoons$ agmatine + CO₂

Hence, this enzyme has one substrate, L-arginine, and two products, agmatine and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is L-arginine carboxy-lyase (agmatine-forming). Other names in common use include SpeA, and L-arginine carboxy-lyase. This enzyme participates in urea cycle and metabolism of amino groups and glutamate metabolism. It employs one cofactor, pyridoxal phosphate.

tructural studies

As of late 2007, 5 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1MT1, PDB link|1N13, PDB link|1N2M, PDB link|2NV9, and PDB link|2NVA.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9024-77-5."

Gene Ontology (GO) codes