Acetolactate decarboxylase

In enzymology, an acetolactate decarboxylase (EC number|4.1.1.5) is an enzyme that catalyzes the chemical reaction

:(S)-2-hydroxy-2-methyl-3-oxobutanoate $ightleftharpoons$ (R)-2-acetoin + CO₂

Hence, this enzyme has one substrate, (S)-2-hydroxy-2-methyl-3-oxobutanoate, and two products, (R)-2-acetoin and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase [(R)-2-acetoin-forming] . Other names in common use include alpha-acetolactate decarboxylase, and (S)-2-hydroxy-2-methyl-3-oxobutanoate carboxy-lyase. This enzyme participates in butanoate metabolism and c5-branched dibasic acid metabolism.

tructural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code PDB link|1XV2.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9025-02-9."

Gene Ontology (GO) codes