- (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase
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(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase Identifiers EC number 4.1.3.35 CAS number 71343-09-4 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase (EC 4.1.3.35) is an enzyme that catalyzes the chemical reaction
- (1-hydroxycyclohexan-1-yl)acetyl-CoA
acetyl-CoA + cyclohexanone
Hence, this enzyme has one substrate, (1-hydroxycyclohexan-1-yl)acetyl-CoA, and two products, acetyl-CoA and cyclohexanone.
This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase (acetyl-CoA-forming). This enzyme is also called (1-hydroxycyclohexan-1-yl)acetyl-CoA cyclohexanone-lyase.
References
- Ougham HJ, Trudgill PW (1982). "Metabolism of cyclohexaneacetic acid and cyclohexanebutyric acid by Arthrobacter sp. strain CA1". J. Bacteriol. 150 (3): 1172–82. PMC 216338. PMID 7076617. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=216338.
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