Deacetylisoipecoside synthase

Deacetylisoipecoside synthase
deacetylisoipecoside synthase
Identifiers
EC number 4.3.3.3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a deacetylisoipecoside synthase (EC 4.3.3.3) is an enzyme that catalyzes the chemical reaction

deacetylisoipecoside + H2O \rightleftharpoons dopamine + secologanin

Thus, the two substrates of this enzyme are deacetylisoipecoside and H2O, whereas its two products are dopamine and secologanin.

This enzyme belongs to the family of lyases, specifically amine lyases, which cleave carbon-nitrogen bonds. The systematic name of this enzyme class is deacetylisoipecoside dopamine-lyase (secologanin-forming). This enzyme is also called deacetylisoipecoside dopamine-lyase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

  • MH (1997). "Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii". Phytochemistry 45 (3): 477–484. doi:10.1016/S0031-9422(96)00828-X. 
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