- Maleylpyruvate isomerase
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maleylpyruvate isomerase Identifiers EC number 5.2.1.4 CAS number 9023-77-2 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a maleylpyruvate isomerase (EC 5.2.1.4) is an enzyme that catalyzes the chemical reaction
- 3-maleylpyruvate
3-fumarylpyruvate
Hence, this enzyme has one substrate, 3-maleylpyruvate, and one product, 3-fumarylpyruvate.
This enzyme belongs to the family of isomerases, specifically cis-trans isomerases. The systematic name of this enzyme class is 3-maleylpyruvate cis-trans-isomerase. This enzyme participates in tyrosine metabolism.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2NSF and 2NSG.
References
- Lack L (1961). "Enzymic cis-trans isomerization of maleylpyruvic acid". J. Biol. Chem. 236: 2835–2840. PMID 14461395.
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