4-hydroxyproline epimerase
- 4-hydroxyproline epimerase
In enzymology, a 4-hydroxyproline epimerase (EC number|5.1.1.8) is an enzyme that catalyzes the chemical reaction
:trans-4-hydroxy-L-proline cis-4-hydroxy-D-proline
Hence, this enzyme has one substrate, trans-4-hydroxy-L-proline, and one product, cis-4-hydroxy-D-proline.
This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on amino acids and derivatives. The systematic name of this enzyme class is 4-hydroxyproline 2-epimerase. Other names in common use include hydroxyproline epimerase, hydroxyproline 2-epimerase, and L-hydroxyproline epimerase. This enzyme participates in arginine and proline metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|9024-23-1."
Gene Ontology (GO) codes
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List of EC numbers (EC 5) — This list contains a list of EC numbers for the fifth group, EC 5, isomerases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. =EC 5.1: Epimerases and… … Wikipedia
Amino acid — This article is about the class of chemicals. For the structures and properties of the standard proteinogenic amino acids, see Proteinogenic amino acid. The generic structure of an alpha amino acid in its unionized form … Wikipedia
racemase — An enzyme capable of catalyzing racemization, i.e., inversions of asymmetric groups; when more than one center of asymmetry is present, “epimerase” is used ( e.g., hydroxyproline, ribulose phosphate). * * * rac·e·mase ras ə .mās n any of various… … Medical dictionary
