4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase

In enzymology, a 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (EC number|5.3.1.17) is an enzyme that catalyzes the chemical reaction

:4-deoxy-L-threo-5-hexosulose uronate $ightleftharpoons$ 3-deoxy-D-glycero-2,5-hexodiulosonate

Hence, this enzyme has one substrate, 4-deoxy-L-threo-5-hexosulose uronate, and one product, 3-deoxy-D-glycero-2,5-hexodiulosonate.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is 4-deoxy-L-threo-5-hexosulose-uronate aldose-ketose-isomerase. This enzyme is also called 4-deoxy-L-threo-5-hexulose uronate isomerase. This enzyme participates in pentose and glucuronate interconversions.

tructural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes PDB link|1X8M, PDB link|1XRU, and PDB link|1YWK.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37318-44-8."

Gene Ontology (GO) codes