Saccharopine dehydrogenase (NAD+, L-glutamate-forming)
- Saccharopine dehydrogenase (NAD+, L-glutamate-forming)
In enzymology, a saccharopine dehydrogenase (NAD+, L-glutamate-forming) (EC number|1.5.1.9) is an enzyme that catalyzes the chemical reaction
:N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O L-glutamate + 2-aminoadipate 6-semialdehyde + NADH + H+
The 3 substrates of this enzyme are N6-(L-1,3-dicarboxypropyl)-L-lysine, NAD+, and H2O, whereas its 4 products are L-glutamate, 2-aminoadipate 6-semialdehyde, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is N6-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase (L-glutamate-forming). Other names in common use include dehydrogenase, saccharopine (nicotinamide adenine dinucleotide,, glutamate-forming), saccharopin dehydrogenase, NAD+ oxidoreductase (L-2-aminoadipic-delta-semialdehyde and, glutamate forming), aminoadipic semialdehyde synthase, saccharopine dehydrogenase (NAD+, L-glutamate-forming), 6-N-(L-1,3-dicarboxypropyl)-L-lysine:NAD+ oxidoreductase, and (L-glutamate-forming). This enzyme participates in lysine degradation.
References
*
*
External links
::"The CAS registry number for this enzyme class is CAS registry|37256-26-1."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
saccharopine dehydrogenase (NAD+ L-glutamate-forming) — sac·cha·ro·pine de·hy·dro·gen·ase (NAD+, L glu·ta·mate form·ing) (sakґə ro pēn″ de hiґdro jən ās glooґtə māt formґing) [EC 1.5.1.9] official nomenclature for saccharopine dehydrogenase … Medical dictionary
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) — In enzymology, a saccharopine dehydrogenase (NADP+, L glutamate forming) (EC number|1.5.1.10) is an enzyme that catalyzes the chemical reaction:N6 (L 1,3 dicarboxypropyl) L lysine + NADP+ + H2O ightleftharpoons L glutamate + L 2 aminoadipate 6… … Wikipedia
saccharopine dehydrogenase — sac·cha·ro·pine de·hy·dro·gen·ase (sakґə ro pēn″ de hiґdro jən ās) an enzyme activity that catalyzes oxidative cleavage of saccharopine to form α aminoadipate semialdehyde and glutamate, using NAD+ as an electron… … Medical dictionary
List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH … Wikipedia
Oxidoreductase — In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule (the reductant, also called the hydrogen or electron donor) to another (the oxidant, also called the hydrogen or electron acceptor). This… … Wikipedia
Creatine kinase — Crystals of creatine kinase Creatine kinase (CK), also known as creatine phosphokinase (CPK) or phospho creatine kinase (and sometimes incorrectly as creatinine kinase), is an enzyme (EC 2.7.3.2) expressed by various tissues and cell types. CK… … Wikipedia
