Nitroalkane oxidase

nitroethane oxidase
Identifiers
EC number	1.7.3.1
CAS number	9029-36-1
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a nitroalkane oxidase (EC 1.7.3.1) is an enzyme that catalyzes the chemical reaction

a nitroalkane + H₂O + O₂ $\rightleftharpoons$ an aldehyde or ketone + nitrite + H₂O₂

The 3 substrates of this enzyme are nitroalkane, H₂O, and O₂, whereas its 4 products are aldehyde, ketone, nitrite, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with oxygen as acceptor. The systematic name of this enzyme class is nitroalkane:oxygen oxidoreductase. Other names in common use include nitroethane oxidase, NAO, and nitroethane:oxygen oxidoreductase. This enzyme participates in nitrogen metabolism.

References

• LITTLE HN (1951). "Oxidation of nitroethane by extracts from Neurospora". J. Biol. Chem. 193 (1): 347–58. PMID 14907722. 
• Kido T, Hashizume K, Soda K (1978). "Purification and properties of nitroalkane oxidase from Fusarium oxysporum". J. Bacteriol. 133 (1): 53–8. PMC 221975. PMID 22538. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=221975. 
• Daubner SC, Gadda G, Valley MP, Fitzpatrick PF (2002). "Cloning of nitroalkane oxidase from Fusarium oxysporum identifies a new member of the acyl-CoA dehydrogenase superfamily". Proc. Natl. Acad. Sci. U. S. A. 99 (5): 2702–7. doi:10.1073/pnas.052527799. PMC 122411. PMID 11867731. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=122411. 
• Fitzpatrick PF, Orville AM, Nagpal A, Valley MP (2005). "Nitroalkane oxidase, a carbanion-forming flavoprotein homologous to acyl-CoA dehydrogenase". Arch. Biochem. Biophys. 433 (1): 157–65. doi:10.1016/j.abb.2004.08.021. PMID 15581574. 
• Valley MP, Tichy SE, Fitzpatrick PF (2005). "Establishing the kinetic competency of the cationic imine intermediate in nitroalkane oxidase". J. Am. Chem. Soc. 127 (7): 2062–6. doi:10.1021/ja043542f. PMC 1630679. PMID 15713081. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1630679. 

This EC 1.7 enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Oxidoreductase stubs EC 1.7.3 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем решить контрольную работу Lovey (album) Jan Reinås Look at other dictionaries: Nitro compound — The structure of the nitro group Nitro compounds are organic compounds that contain one or more nitro functional groups ( NO2). They are often highly explosive, especially when the compound contains more than one nitro group and is impure. The… …   Wikipedia List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia Kinetic isotope effect — The kinetic isotope effect (KIE) is the ratio of reaction rates of two different isotopically labeled molecules in a chemical reaction. It is also called isotope fractionation, although this term is somewhat broader in meaning. A KIE involving… …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”