- FADS2
protein
Name=fatty acid desaturase 2
caption=
width=
HGNCid=3575
Symbol=FADS2
AltSymbols=LLCDL2
EntrezGene=9415
OMIM=606149
RefSeq=NM_004265
UniProt=O95864
PDB=
ECnumber=1.14.19.3
Chromosome=11
Arm=q
Band=12.2
LocusSupplementaryData=FADS2 is a
human gene .The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members
FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.cite web | title = Entrez Gene: FADS1 fatty acid desaturase 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3992| accessdate = ]A recent study found that FADS2, along with
breastfeeding , adds about 7intelligence quotient (IQ) points to those with the "C" version of the gene. Those with the "G" version see no advantage. [ [http://www.physorg.com/news113505546.html Gene governs IQ boost from breastfeeding] ] cite journal |author=Caspi A, Williams B, Kim-Cohen J, "et al" |title=Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism |journal= |volume= |issue= |pages= |year=2007 |pmid=17984066 |doi=10.1073/pnas.0704292104]References
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