Glutathione-cystine transhydrogenase

Glutathione-cystine transhydrogenase

In enzymology, a glutathione---cystine transhydrogenase (EC number|1.8.4.4) is an enzyme that catalyzes the chemical reaction

:2 glutathione + cystine ightleftharpoons glutathione disulfide + 2 cysteine

Thus, the two substrates of this enzyme are glutathione and cystine, whereas its two products are glutathione disulfide and cysteine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with a disulfide as acceptor. The systematic name of this enzyme class is glutathione:cystine oxidoreductase. Other names in common use include GSH-cystine transhydrogenase, and NADPH-dependent GSH-cystine transhydrogenase. This enzyme participates in cysteine metabolism and glutathione metabolism.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37256-49-8."

Gene Ontology (GO) codes


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  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Cysteine metabolism — refers to the biological pathways that consume or create cysteine. The pathways of different amino acids and other metabolites interweave and overlap to creating complex systems. Human cysteine metabolism In human cysteine metabolism, L cysteine… …   Wikipedia

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