Quercetin 2,3-dioxygenase

Quercetin 2,3-dioxygenase

In enzymology, a quercetin 2,3-dioxygenase (EC number|1.13.11.24) is an enzyme that catalyzes the chemical reaction

:quercetin + O2 ightleftharpoons 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO + H+

Thus, the two substrates of this enzyme are quercetin and O2, whereas its 3 products are 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate, CO, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O2 as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O2. The systematic name of this enzyme class is quercetin:oxygen 2,3-oxidoreductase (decyclizing). Other names in common use include quercetinase, and flavonol 2,4-oxygenase. It has 2 cofactors: iron, and Copper.

tructural studies

As of late 2007, 6 crystal structures have been solved for this class of enzymes, with PDB accession codes PDB link|1GQG, PDB link|1GQH, PDB link|1H1I, PDB link|1H1M, PDB link|1JUH, and PDB link|2H0V.

References

*
*
*

External links

::"The CAS registry number for this enzyme class is CAS registry|9075-67-6."

Gene Ontology (GO) codes


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Quercetin — IUPAC name 2 (3,4 dihydroxyphenyl) 3,5,7 trihydroxy 4H chromen 4 one …   Wikipedia

  • List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia

  • Catechin — IUPAC name (2R,3S) 2 (3,4 dihydroxyphenyl) 3,4 dihydro 2H chromene 3,5,7 …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”