Methanosarcina-phenazine hydrogenase

Methanosarcina-phenazine hydrogenase
Identifiers
EC number	1.12.98.3
CAS number	9027-05-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles

In enzymology, a Methanosarcina-phenazine hydrogenase (EC 1.12.98.3) is an enzyme that catalyzes the chemical reaction

H₂ + 2-(2,3-dihydropentaprenyloxy)phenazine $\rightleftharpoons$ 2-dihydropentaprenyloxyphenazine

Thus, the two substrates of this enzyme are H₂ and 2-(2,3-dihydropentaprenyloxy)phenazine, whereas its product is 2-dihydropentaprenyloxyphenazine.

This enzyme belongs to the family of oxidoreductases, specifically those acting on hydrogen as donor with other, known, acceptors. The systematic name of this enzyme class is hydrogen:2-(2,3-dihydropentaprenyloxy)phenazine oxidoreductase. Other names in common use include methanophenazine hydrogenase, and methylviologen-reducing hydrogenase.

References

• Abken HJ, Tietze M, Brodersen J, Baumer S, Beifuss U, Deppenmeier U (1998). "Isolation and characterization of methanophenazine and function of phenazines in membrane-bound electron transport of Methanosarcina mazei Go1". J. Bacteriol. 180 (8): 2027–32. PMC 107126. PMID 9555882. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=107126. 
• Deppenmeier U, Lienard T, Gottschalk G (1999). "Novel reactions involved in energy conservation by methanogenic archaea". FEBS. Lett. 457 (3): 291–7. doi:10.1016/S0014-5793(99)01026-1. PMID 10471795. 
• Beifuss U, Tietze M, Baumer S, Deppenmeier U (2000). "Methanophenazine: Structure, Total Synthesis, and Function of a New Cofactor from Methanogenic Archaea This work was supported by the Deutsche Forschungsgemeinschaft (Sonderforschungsbereich 416; grants De 488/6-1 and De 488/4-2) and the Fonds der Chemischen Industrie We are grateful to Drs. J. Paust and H. Jaedicke (BASF AG, Ludwigshafen) and Dr. R. K. Muller (Hoffmann-La Roche Ltd., Basel) for generously providing chemicals". Angew. Chem. Int. Ed. Engl. 39 (14): 2470–2472. doi:10.1002/1521-3773(20000717)39:14<2470::AID-ANIE2470>3.0.CO;2-R. PMID 10941105. 

This EC 1.12 enzyme-related article is a stub. You can help Wikipedia by expanding it.v · Categories: Oxidoreductase stubs EC 1.12.98 Enzymes of unknown structure Wikimedia Foundation. 2010. Игры ⚽ Поможем сделать НИР Perils of the Wilderness Zhu Yi Look at other dictionaries: Hydrogenase — A hydrogenase is an enzyme that catalyses the reversible oxidation of molecular hydrogen (H2). Hydrogenases play a vital role in anaerobic metabolism. [cite journal | author=Adams, M.W.W. and Stiefel, E.I. | title=Biological hydrogen production:… …   Wikipedia Methanophenazine — IUPAC name 2 {[(3S,6E,10E,14E) 3,7,11,15,19 pentamethylicosa 6,10,14,18 tetraen 1 yl]oxy}phen …   Wikipedia List of EC numbers (EC 1) — This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.EC 1.1 Acting on the CH OH …   Wikipedia 18+ © Academic, 2000-2024 Contact us: Technical Support, Advertising Dictionaries export, created on PHP, Joomla, Drupal, WordPress, MODx. Mark and share Search through all dictionaries Translate… Search Internet Share the article and excerpts Direct link … Do a right-click on the link above and select “Copy Link”