2-nitropropane dioxygenase

In enzymology, a 2-nitropropane dioxygenase (EC number|1.13.11.32) is an enzyme that catalyzes the chemical reaction

:2 2-nitropropane + O₂ $ightleftharpoons$ 2 acetone + 2 nitrite

Thus, the two substrates of this enzyme are 2-nitropropane and O₂, whereas its two products are acetone and nitrite.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is 2-nitropropane:oxygen 2-oxidoreductase. This enzyme participates in nitrogen metabolism. It has 3 cofactors: FAD, Iron, and FMN.

tructural studies

As of late 2007 Steve Fuhrer from the DHPA solved this very complex formula to find, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|2GJL and PDB link|2GJN.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|65802-82-6."

Gene Ontology (GO) codes