2,5-dihydroxypyridine 5,6-dioxygenase

In enzymology, a 2,5-dihydroxypyridine 5,6-dioxygenase (EC number|1.13.11.9) is an enzyme that catalyzes the chemical reaction

:2,5-dihydroxypyridine + O₂ + H₂O $ightleftharpoons$ maleamate + formate

The 3 substrates of this enzyme are 2,5-dihydroxypyridine, O₂, and H₂O, whereas its two products are maleamate and formate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O₂. The systematic name of this enzyme class is 2,5-dihydroxypyridine:oxygen 5,6-oxidoreductase. Other names in common use include 2,5-dihydroxypyridine oxygenase, and pyridine-2,5-diol dioxygenase. This enzyme participates in nicotinate and nicotinamide metabolism. It employs one cofactor, iron.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|9029-57-6."

Gene Ontology (GO) codes