- ALOX15
Arachidonate 15-lipoxygenase, also known as ALOX15, is a human
gene .PBB_Summary
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summary_text =Further reading
PBB_Further_reading
citations =
*cite journal | author=Kelavkar U, Glasgow W, Eling TE |title=The effect of 15-lipoxygenase-1 expression on cancer cells. |journal=Current urology reports |volume=3 |issue= 3 |pages= 207–14 |year= 2003 |pmid= 12084190 |doi=
*cite journal | author=Sigal E, Dicharry S, Highland E, Finkbeiner WE |title=Cloning of human airway 15-lipoxygenase: identity to the reticulocyte enzyme and expression in epithelium. |journal=Am. J. Physiol. |volume=262 |issue= 4 Pt 1 |pages= L392–8 |year= 1992 |pmid= 1566855 |doi=
*cite journal | author=Funk CD, Funk LB, FitzGerald GA, Samuelsson B |title=Characterization of human 12-lipoxygenase genes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 9 |pages= 3962–6 |year= 1992 |pmid= 1570320 |doi=
*cite journal | author=Izumi T, Rådmark O, Jörnvall H, Samuelsson B |title=Purification of two forms of arachidonate 15-lipoxygenase from human leukocytes. |journal=Eur. J. Biochem. |volume=202 |issue= 3 |pages= 1231–8 |year= 1992 |pmid= 1662607 |doi=
*cite journal | author=Conrad DJ, Kuhn H, Mulkins M, "et al." |title=Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=89 |issue= 1 |pages= 217–21 |year= 1992 |pmid= 1729692 |doi=
*cite journal | author=Lei ZM, Rao CV |title=The expression of 15-lipoxygenase gene and the presence of functional enzyme in cytoplasm and nuclei of pregnancy human myometria. |journal=Endocrinology |volume=130 |issue= 2 |pages= 861–70 |year= 1992 |pmid= 1733732 |doi=
*cite journal | author=Izumi T, Rådmark O, Samuelsson B |title=Purification of 15-lipoxygenase from human leukocytes, evidence for the presence of isozymes. |journal=Adv. Prostaglandin Thromboxane Leukot. Res. |volume=21A |issue= |pages= 101–4 |year= 1991 |pmid= 1825526 |doi=
*cite journal | author=Sloane DL, Leung R, Craik CS, Sigal E |title=A primary determinant for lipoxygenase positional specificity. |journal=Nature |volume=354 |issue= 6349 |pages= 149–52 |year= 1991 |pmid= 1944593 |doi= 10.1038/354149a0
*cite journal | author=Nadel JA, Conrad DJ, Ueki IF, "et al." |title=Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells. |journal=J. Clin. Invest. |volume=87 |issue= 4 |pages= 1139–45 |year= 1991 |pmid= 2010530 |doi=
*cite journal | author=Kroschwald P, Kroschwald A, Kühn H, "et al." |title=Occurrence of the erythroid cell specific arachidonate 15-lipoxygenase in human reticulocytes. |journal=Biochem. Biophys. Res. Commun. |volume=160 |issue= 2 |pages= 954–60 |year= 1989 |pmid= 2719708 |doi=
*cite journal | author=Sigal E, Nadel JA |title=Arachidonic acid 15-lipoxygenase and airway epithelium. Biologic effects and enzyme purification. |journal=Am. Rev. Respir. Dis. |volume=138 |issue= 6 Pt 2 |pages= S35–40 |year= 1989 |pmid= 3202520 |doi=
*cite journal | author=Sigal E, Craik CS, Highland E, "et al." |title=Molecular cloning and primary structure of human 15-lipoxygenase. |journal=Biochem. Biophys. Res. Commun. |volume=157 |issue= 2 |pages= 457–64 |year= 1989 |pmid= 3202857 |doi=
*cite journal | author=Sigal E, Grunberger D, Craik CS, "et al." |title=Arachidonate 15-lipoxygenase (omega-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases. |journal=J. Biol. Chem. |volume=263 |issue= 11 |pages= 5328–32 |year= 1988 |pmid= 3356688 |doi=
*cite journal | author=Nassar GM, Morrow JD, Roberts LJ, "et al." |title=Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. |journal=J. Biol. Chem. |volume=269 |issue= 44 |pages= 27631–4 |year= 1994 |pmid= 7961680 |doi=
*cite journal | author=Kritzik MR, Ziober AF, Dicharry S, "et al." |title=Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene. |journal=Biochim. Biophys. Acta |volume=1352 |issue= 3 |pages= 267–81 |year= 1997 |pmid= 9224951 |doi=
*cite journal | author=Brinckmann R, Schnurr K, Heydeck D, "et al." |title=Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme. |journal=Blood |volume=91 |issue= 1 |pages= 64–74 |year= 1998 |pmid= 9414270 |doi=
*cite journal | author=Kelavkar U, Wang S, Montero A, "et al." |title=Human 15-lipoxygenase gene promoter: analysis and identification of DNA binding sites for IL-13-induced regulatory factors in monocytes. |journal=Mol. Biol. Rep. |volume=25 |issue= 3 |pages= 173–82 |year= 1998 |pmid= 9700053 |doi=
*cite journal | author=Roy B, Cathcart MK |title=Induction of 15-lipoxygenase expression by IL-13 requires tyrosine phosphorylation of Jak2 and Tyk2 in human monocytes. |journal=J. Biol. Chem. |volume=273 |issue= 48 |pages= 32023–9 |year= 1998 |pmid= 9822675 |doi=
*cite journal | author=Kratky D, Lass A, Abuja PM, "et al." |title=A sensitive chemiluminescence method to measure the lipoxygenase catalyzed oxygenation of complex substrates. |journal=Biochim. Biophys. Acta |volume=1437 |issue= 1 |pages= 13–22 |year= 1999 |pmid= 9931410 |doi=
*cite journal | author=Kelavkar UP, Badr KF |title=Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 8 |pages= 4378–83 |year= 1999 |pmid= 10200270 |doi=PBB_Controls
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