ARF1

ADP-ribosylation factor 1, also known as ARF1, is a human gene.

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summary_text = ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [cite web | title = Entrez Gene: ARF1 ADP-ribosylation factor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=375| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lee CM, Haun RS, Tsai SC, "et al." |title=Characterization of the human gene encoding ADP-ribosylation factor 1, a guanine nucleotide-binding activator of cholera toxin. |journal=J. Biol. Chem. |volume=267 |issue= 13 |pages= 9028–34 |year= 1992 |pmid= 1577740 |doi=
*cite journal | author=Serafini T, Orci L, Amherdt M, "et al." |title=ADP-ribosylation factor is a subunit of the coat of Golgi-derived COP-coated vesicles: a novel role for a GTP-binding protein. |journal=Cell |volume=67 |issue= 2 |pages= 239–53 |year= 1991 |pmid= 1680566 |doi=
*cite journal | author=Kahn RA, Kern FG, Clark J, "et al." |title=Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins. |journal=J. Biol. Chem. |volume=266 |issue= 4 |pages= 2606–14 |year= 1991 |pmid= 1899243 |doi=
*cite journal | author=Stearns T, Willingham MC, Botstein D, Kahn RA |title=ADP-ribosylation factor is functionally and physically associated with the Golgi complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=87 |issue= 3 |pages= 1238–42 |year= 1990 |pmid= 2105501 |doi=
*cite journal | author=Bobak DA, Nightingale MS, Murtagh JJ, "et al." |title=Molecular cloning, characterization, and expression of human ADP-ribosylation factors: two guanine nucleotide-dependent activators of cholera toxin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 16 |pages= 6101–5 |year= 1989 |pmid= 2474826 |doi=
*cite journal | author=Greasley SE, Jhoti H, Teahan C, "et al." |title=The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms. |journal=Nat. Struct. Biol. |volume=2 |issue= 9 |pages= 797–806 |year= 1995 |pmid= 7552752 |doi=
*cite journal | author=Welsh CF, Moss J, Vaughan M |title=ADP-ribosylation factors: a family of approximately 20-kDa guanine nucleotide-binding proteins that activate cholera toxin. |journal=Mol. Cell. Biochem. |volume=138 |issue= 1-2 |pages= 157–66 |year= 1995 |pmid= 7898460 |doi=
*cite journal | author=Greasley S, Jhoti H, Fensome AC, "et al." |title=Crystallization and preliminary X-ray diffraction studies on ADP-ribosylation factor 1. |journal=J. Mol. Biol. |volume=244 |issue= 5 |pages= 651–3 |year= 1995 |pmid= 7990146 |doi= 10.1006/jmbi.1994.1759
*cite journal | author=Amor JC, Harrison DH, Kahn RA, Ringe D |title=Structure of the human ADP-ribosylation factor 1 complexed with GDP. |journal=Nature |volume=372 |issue= 6507 |pages= 704–8 |year= 1995 |pmid= 7990966 |doi= 10.1038/372704a0
*cite journal | author=Dascher C, Balch WE |title=Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus. |journal=J. Biol. Chem. |volume=269 |issue= 2 |pages= 1437–48 |year= 1994 |pmid= 8288610 |doi=
*cite journal | author=Rümenapp U, Geiszt M, Wahn F, "et al." |title=Evidence for ADP-ribosylation-factor-mediated activation of phospholipase D by m3 muscarinic acetylcholine receptor. |journal=Eur. J. Biochem. |volume=234 |issue= 1 |pages= 240–4 |year= 1996 |pmid= 8529647 |doi=
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Hirai M, Kusuda J, Hashimoto K |title=Assignment of human ADP ribosylation factor (ARF) genes ARF1 and ARF3 to chromosomes 1q42 and 12q13, respectively. |journal=Genomics |volume=34 |issue= 2 |pages= 263–5 |year= 1997 |pmid= 8661066 |doi= 10.1006/geno.1996.0283
*cite journal | author=Kanoh H, Williger BT, Exton JH |title=Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes. |journal=J. Biol. Chem. |volume=272 |issue= 9 |pages= 5421–9 |year= 1997 |pmid= 9038142 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Shome K, Vasudevan C, Romero G |title=ARF proteins mediate insulin-dependent activation of phospholipase D. |journal=Curr. Biol. |volume=7 |issue= 6 |pages= 387–96 |year= 1997 |pmid= 9197239 |doi=
*cite journal | author=Frank S, Upender S, Hansen SH, Casanova JE |title=ARNO is a guanine nucleotide exchange factor for ADP-ribosylation factor 6. |journal=J. Biol. Chem. |volume=273 |issue= 1 |pages= 23–7 |year= 1998 |pmid= 9417041 |doi=
*cite journal | author=Betz SF, Schnuchel A, Wang H, "et al." |title=Solution structure of the cytohesin-1 (B2-1) Sec7 domain and its interaction with the GTPase ADP ribosylation factor 1. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 14 |pages= 7909–14 |year= 1998 |pmid= 9653114 |doi=
*cite journal | author=Kim JH, Lee SD, Han JM, "et al." |title=Activation of phospholipase D1 by direct interaction with ADP-ribosylation factor 1 and RalA. |journal=FEBS Lett. |volume=430 |issue= 3 |pages= 231–5 |year= 1998 |pmid= 9688545 |doi=
*cite journal | author=Huber I, Cukierman E, Rotman M, "et al." |title=Requirement for both the amino-terminal catalytic domain and a noncatalytic domain for in vivo activity of ADP-ribosylation factor GTPase-activating protein. |journal=J. Biol. Chem. |volume=273 |issue= 38 |pages= 24786–91 |year= 1998 |pmid= 9733781 |doi=

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