Progesterone 5alpha-reductase
- Progesterone 5alpha-reductase
In enzymology, a progesterone 5alpha-reductase (EC number|1.3.1.30) is an enzyme that catalyzes the chemical reaction
:5alpha-pregnan-3,20-dione + NADP+ progesterone + NADPH + H+
Thus, the two substrates of this enzyme are 5alpha-pregnan-3,20-dione and NADP+, whereas its 3 products are progesterone, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5alpha-pregnan-3,20-dione:NADP+ 5-oxidoreductase. Other names in common use include steroid 5-alpha-reductase, and Delta4-steroid 5alpha-reductase (progesterone). This enzyme participates in c21-steroid hormone metabolism.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|72412-84-1."
Gene Ontology (GO) codes
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