Long-chain-acyl-CoA dehydrogenase
- Long-chain-acyl-CoA dehydrogenase
In enzymology, a long-chain-acyl-CoA dehydrogenase (EC number|1.3.99.13) is an enzyme that catalyzes the chemical reaction
:acyl-CoA + acceptor 2,3-dehydroacyl-CoA + reduced acceptor
Thus, the two substrates of this enzyme are acyl-CoA and acceptor, whereas its two products are 2,3-dehydroacyl-CoA and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with other acceptors. The systematic name of this enzyme class is long-chain-acyl-CoA:acceptor 2,3-oxidoreductase. Other names in common use include palmitoyl-CoA dehydrogenase, palmitoyl-coenzyme A dehydrogenase, long-chain acyl-coenzyme A dehydrogenase, and long-chain-acyl-CoA:(acceptor) 2,3-oxidoreductase. This enzyme participates in fatty acid metabolism and ppar signaling pathway. It employs one cofactor, FAD.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|59536-74-2."
Gene Ontology (GO) codes
Wikimedia Foundation.
2010.
Look at other dictionaries:
long-chain acyl-CoA dehydrogenase — See acyl CoA dehydrogenase (NADPH) … Medical dictionary
long-chain acyl-CoA dehydrogenase (LCAD) deficiency — a defect in mitochondrial beta oxidation due to a mutation in the gene (locus: 2q34 q35) encoding the acyl CoA dehydrogenase that acts on long chain length fatty acids. It is clinically similar to MCAD deficiency, but urinary excretion is of long … Medical dictionary
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acyl-CoA — Condensation product of a carboxylic acid and coenzyme A; metabolic intermediate of importance, notably in the oxidation and synthesis of fat. SYN: acyl coenzyme A. acyl CoA dehydrogenase (NADPH) … Medical dictionary
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Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency — DiseaseDisorder infobox Name = Long chain 3 hydroxyacyl coenzyme A dehydrogenase deficiency ICD10 = ICD9 = ICD9|277.85 ICDO = Caption = OMIM = 600890 MedlinePlus = eMedicineSubj = ped eMedicineTopic = 1284 DiseasesDB = Long chain 3 hydroxyacyl… … Wikipedia
Medium-chain acyl-coenzyme A dehydrogenase deficiency — (MCAD) Classification and external resources ICD 9 277.85 OMIM 201450 … Wikipedia
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