Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)
- Enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)
In enzymology, an enoyl- [acyl-carrier-protein] reductase (NADPH, B-specific) (EC number|1.3.1.10) is an enzyme that catalyzes the chemical reaction
:acyl- [acyl-carrier-protein] + NADP+ trans-2,3-dehydroacyl- [acyl-carrier-protein] + NADPH + H+
Thus, the two substrates of this enzyme are [acyl- [acyl-carrier-protein] and NADP+, whereas its 3 products are [trans-2,3-dehydroacyl- [acyl-carrier-protein] , NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is acyl- [acyl-carrier-protein] :NADP+ oxidoreductase (B-specific). Other names in common use include acyl-ACP dehydrogenase, reductase, enoyl- [acyl carrier protein] (reduced nicotinamide, adenine dinucleotide phosphate), NADPH 2-enoyl Co A reductase, enoyl acyl-carrier-protein reductase, enoyl-ACP reductase, and enoyl- [acyl-carrier-protein] reductase (NADPH, B-specific). This enzyme participates in fatty acid biosynthesis.
tructural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes PDB link|1ULU and PDB link|2YW9.
References
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External links
::"The CAS registry number for this enzyme class is CAS registry|37251-09-5."
Gene Ontology (GO) codes
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2010.
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