- Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
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cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase Identifiers EC number 1.3.1.49 CAS number 118390-61-7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49) is an enzyme that catalyzes the chemical reaction
- (+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD+ phenanthrene-3,4-diol + NADH + H+
Thus, the two substrates of this enzyme are (+)-cis-3,4-dihydrophenanthrene-3,4-diol and NAD+, whereas its 3 products are phenanthrene-3,4-diol, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.
References
- Nagao K, Takizawa N and Kiyahara H (1988). "Purification and properties of cis-phenanthrene dihydrodiol dehydrogenase in Alcaligenes faecalis AFK2". Agric. Biol. Chem. 52 (10): 2621–2623. doi:10.1271/bbb1961.52.2621.
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