2-dehydropantolactone reductase (B-specific)

In enzymology, a 2-dehydropantolactone reductase (B-specific) (EC number|1.1.1.214) is an enzyme that catalyzes the chemical reaction

:(R)-pantolactone + NADP⁺ $ightleftharpoons$ 2-dehydropantolactone + NADPH + H⁺

Thus, the two substrates of this enzyme are (R)-pantolactone and NADP⁺, whereas its 3 products are 2-dehydropantolactone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-pantolactone:NADP+ oxidoreductase (B-specific). Other names in common use include 2-oxopantoyl lactone reductase, 2-ketopantoyl lactone reductase, ketopantoyl lactone reductase, and 2-dehydropantoyl-lactone reductase (B-specific).

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|37211-75-9."

Gene Ontology (GO) codes