Omega-hydroxydecanoate dehydrogenase

Omega-hydroxydecanoate dehydrogenase
omega-hydroxydecanoate dehydrogenase
Identifiers
EC number 1.1.1.66
CAS number 9028-65-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, an omega-hydroxydecanoate dehydrogenase (EC 1.1.1.66) is an enzyme that catalyzes the chemical reaction

10-hydroxydecanoate + NAD+ ⇌ 10-oxodecanoate + NADH + H+

Thus, the two substrates of this enzyme are 10-hydroxydecanoate and NAD+, whereas its 3 products are 10-oxodecanoate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 10-hydroxydecanoate:NAD+ 10-oxidoreductase.

References

  • Kamei S, Wakabayashi K and Shimazono M (Tokyo). "omega-Oxidation of fatty acids in vitro. II. omega-Hydroxy fatty acid-NAD oxidoreductase". J. Biochem.: 72–76. PMID 14202238. 
  • Mitz MA and Henrikson RL (1961). "Omega hydroxy fatty acid dehydrogenase". Biochim. Biophys. Acta 46: 45–50. doi:10.1016/0006-3002(61)90644-8. PMID 13771448. 
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