Hydroxycyclohexanecarboxylate dehydrogenase

In enzymology, a hydroxycyclohexanecarboxylate dehydrogenase (EC number|1.1.1.166) is an enzyme that catalyzes the chemical reaction

:(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD⁺ $ightleftharpoons$ (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H⁺

Thus, the two substrates of this enzyme are (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate and NAD⁺, whereas its 3 products are (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase. Other names in common use include dihydroxycyclohexanecarboxylate dehydrogenase, and (-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD+ oxidoreductase.

References

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External links

::"The CAS registry number for this enzyme class is CAS registry|55467-53-3."

Gene Ontology (GO) codes