- Cyclohexane-1,2-diol dehydrogenase
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cyclohexane-1,2-diol dehydrogenase Identifiers EC number 1.1.1.174 CAS number 62628-27-7 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view KEGG KEGG entry MetaCyc metabolic pathway PRIAM profile PDB structures RCSB PDB PDBe PDBsum Gene Ontology AmiGO / EGO Search PMC articles PubMed articles In enzymology, a cyclohexane-1,2-diol dehydrogenase (EC 1.1.1.174) is an enzyme that catalyzes the chemical reaction
- trans-cyclohexane-1,2-diol + NAD+
2-hydroxycyclohexan-1-one + NADH + H+
Thus, the two substrates of this enzyme are trans-cyclohexane-1,2-diol and NAD+, whereas its 3 products are 2-hydroxycyclohexan-1-one, NADH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is trans-cyclohexane-1,2-diol:NAD+ 1-oxidoreductase. This enzyme participates in caprolactam degradation.
References
- Davey JF, Trudgill PW (1977). "The metabolism of trans-cyclohexan-1,2-diol by an Acinetobacter species". Eur. J. Biochem. 74 (1): 115–27. doi:10.1111/j.1432-1033.1977.tb11373.x. PMID 856571.
This EC 1.1.1 enzyme-related article is a stub. You can help Wikipedia by expanding it. - trans-cyclohexane-1,2-diol + NAD+
