SSR-149415

Drugbox
IUPAC_name = (2S,4R)-1-(5-chloro-1-((2,4-dimethoxyphenyl)sulfonyl)-3-(2-methoxyphenyl) -2-oxo-2,3-dihydro-1H-indol-3-yl)-4-hydroxy-N,N-dimethyl-2-pyrrolidinecarboxamide




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C=30 | H=32 | Cl = 1 | N=3 | O=8 | S=1
molecular_weight = 630.11
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SSR-149415 is a selective and orally active non-peptide antagonist of vasopressin V(1b) receptor.cite journal | author = Griebel G, Simiand J, Serradeil-Le Gal C, Wagnon J, Pascal M, Scatton B, Maffrand JP, Soubrie P | title = Anxiolytic- and antidepressant-like effects of the non-peptide vasopressin V1b receptor antagonist, SSR149415, suggest an innovative approach for the treatment of stress-related disorders | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 99 | issue = 9 | pages = 6370–5 | year = 2002 | pmid = 11959912 | doi = 10.1073/pnas.092012099 | issn = ] The drug is currently in clinical trails for treatment of anxiety and depression.cite journal | author = Serradeil-Le Gal C, Wagnon J, Tonnerre B, Roux R, Garcia G, Griebel G, Aulombard A | title = An overview of SSR149415, a selective nonpeptide vasopressin V(1b) receptor antagonist for the treatment of stress-related disorders | journal = CNS drug reviews | volume = 11 | issue = 1 | pages = 53–68 | year = 2005 | pmid = 15867952 | doi = | issn = ]

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