Vanilloid

Vanilloid

A vanilloid is a type of nerve receptor which is closely related to cannabinoid receptors.cite journal
journal =European journal of pharmacology
year=2003
month=July
volume=472
issue=1-2
pages=1–21
title=Cannabinoid modulation of peripheral autonomic and sensory neurotransmission.
author=Ralevic V.
pmid=12860468
doi=10.1016/S0014-2999(03)01813-2
]

As a type of nerve receptor, it is activated by a ligand, or neurochemical 'key', which will communicate a sensation within the nervous system. For example, the only vanilloid receptor found as of yet is vanilloid receptor subtype 1 (TRPV1). The specific ligand(s) for this receptor has not yet been found, but the endocannabinoid ligands, N-arachidonoyl-dopamine and arachidonoyl ethanolamide (anandamide or AEA) bind to VR1.

ee also

*Capsaicin
*Endocannabinoid system
*Cannabinoid receptor
*Vanilloid receptor subtype 1

External links

* [http://www.sigmaaldrich.com/sigma/rbi-handbook/sg_ls_cs_rbibook_vanilloid.pdf Vanilloid receptor factbook] ] from Sigma Aldrich.

References


Wikimedia Foundation. 2010.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • vanilloid — noun Any of many organic compounds having a vanillyl based structure …   Wiktionary

  • vanilloid receptor-1 — Receptor found selectively on sensory neurons, resembling (distantly) receptors of the TRP type. Protein (95 kD) with six transmembrane domains having some similarity with SOCS (store operated calcium channels), though VR 1 does not seem to be a… …   Dictionary of molecular biology

  • Discovery and development of TRPV1 antagonists — Chronic pain remains a recognized unmet medical need. Consequently, the search for new analgesic agents is being intensively studied by the pharmaceutical industry. The TRPV1 receptor is an ion channel that has been implicated in mediation of… …   Wikipedia

  • TRPV1 — The Transient receptor potential vanilloid 1 or TRPV1 can refer to the TRP cation channel receptor or the gene which encodes it in Homo sapiens .TRPV1 is a nonselective ligand gated cation channel that may be activated by a wide variety of… …   Wikipedia

  • TRPV1 — Este artículo o sección tiene un estilo difícil de entender para los lectores interesados en el tema. Si puedes, por favor edítalo y contribuye a hacerlo más accesible para el público general, sin eliminar los detalles técnicos que interesan a… …   Wikipedia Español

  • Resiniferatoxin — Chembox new Name = Resiniferatoxin ImageFile = Resiniferatoxin.svg ImageName = IUPACName = Section1 = Chembox Identifiers CASNo = 57444 62 9 PubChem = 104826 MeSHName = resiniferatoxin Section2 = Chembox Properties Formula = C37H40O9 MolarMass =… …   Wikipedia

  • Group C nerve fiber — Infobox Anatomy Name = PAGENAME Latin = GraySubject = GrayPage = Caption = C fiber not labeled, but substantia gelatinosa of Rolando is Rexed lamina II, labeled at upper left. Caption2 = Precursor = System = Artery = Vein = Nerve = Lymph =… …   Wikipedia

  • TRP-Kanäle — Bezeichner Gen Name(n) TRPC, TRPV, TRPM, TRPN, TRPA, TRPP …   Deutsch Wikipedia

  • Ion channel — Not to be confused with: Ion Television or Ion implantation. Schematic diagram of an ion channel. 1 channel domains (typically four per channel), 2 outer vestibule, 3 selectivity filter, 4 diameter of selectivity filter, 5 phosphorylation site, 6 …   Wikipedia

  • Capsaicin — Chembox new ImageFile1 = Capsaicin chemical structure.png ImageSize1 = 250px ImageFile2 = Capsaicin 3D vdW.png ImageSize2 = 250px IUPACName = 8 Methyl N vanillyl trans 6 nonenamide OtherNames = (E) N (4 Hydroxy 3 methoxybenzyl) 8 methylnon 6… …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”