Carbarsone

Drugbox
IUPAC_name = [4-(Carbamoylamino)phenyl] arsonic acid


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CAS_number = 121-59-5
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PubChem= 8480
C = 7 | H = 9 | As = 1 | N = 2 | O = 4
molecular_weight = 260.079 g/mol
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routes_of_administration= Oral

Carbarsone is an arsenic-based antiprotozoal drug which has been used in the treatment of amebiasis and other infections.cite journal |author=SASAKI T, YOKAGAWA M, WYKOFF DE, RITICHIE LS |title=Asymptomatic amebiasis; treatment with atabrine in combination with carbarsone or chiniofon |journal=United States Armed Forces medical journal |volume=7 |issue=3 |pages=363–8 |year=1956 |pmid=13299463 |doi=] cite journal |author=RADKE RA |title=Ameboma of the intestine: an analysis of the disease as presented in 78 collected and 41 previously unreported cases |journal=Ann. Intern. Med. |volume=43 |issue=5 |pages=1048–66 |year=1955 |pmid=13268997 |doi=] cite journal |author=HOEKENGA MT |title=A comparison of aureomycin and carbarsone in the treatment of intestinal amebiasis |journal=Am. J. Trop. Med. Hyg. |volume=31 |issue=4 |pages=423–5 |year=1951 |pmid=14857246 |url=http://www.ajtmh.org/cgi/content/abstract/s1-31/4/423] It was available for use in the United States as a drug for amebiasis as late as 1991. Thereafter, it remained available as an additive for turkey feed for improving weight and controlling Blackhead disease.cite journal |author=McDougald LR |title=Efficacy and compatibility of amprolium and carbarsone against Coccidiosis and blackhead in turkeys |journal=Poult. Sci. |volume=58 |issue=1 |pages=76–80 |year=1979 |pmid=572970 |doi=] cite journal |author=Worden AN, Wood EC |title=The effect of Carbarsone (33.6 per cent w-v p-ureidobenzene arsonic acid) on bodyweight gain, food conversion and tissue arsenic levels of turkey poults |journal=J. Sci. Food Agric. |volume=24 |issue=1 |pages=35–41 |year=1973 |pmid=4696593 |doi=]

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