HLA-DR11

HLA-DR11

HLA-DR11 is genetically linked to HLA-DR52 and HLA-DQ7(3) serotypes.The frequency node for DR11 is in the Levant and Anatolia. This serotype more than others appears to have spread with neolithization of Western Europe. The closely linked DQ7.5 appears to be protective against juvenile diabetes, in which wheat consumption appears to be a risk factor.

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  • HLA-DR52 — is an HLA DR serotype that recognizes gene products of HLA DRB3 locus. There are 3 allele groups that can produce 35 isoforms.DRB3, DRB4, and DRB5 are minor DR beta encoding loci, they have been recognized as having distinct evolution.cite… …   Wikipedia

  • HLA-DR5 — (DR5) is a broad antigen serotype that is further split into HLA DR11 and HLA DR12 antigen serotypes.=Serology=With the exception of a few DRB1* alleles the reactivity of DR5 is relatively poor.=Disease associations=DR5 is associated with… …   Wikipedia

  • HLA-B45 — (B45) is an HLA B serotype. The serotype identifies the B*45 gene allele protein products of HLA B.cite journal | author = Marsh SG, Albert ED, Bodmer WF, et al | title = Nomenclature for factors of the HLA system, 2004 | journal = Tissue… …   Wikipedia

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