P87PIKAP

P87PIKAP: Phosphoinositide-3-kinase adapter protein of 87 kDa

Identifiers

Symbol p87^PIKAP

Alt. symbols p84,PIK3R6

Entrez 146850

HUGO 27101

OMIM 164730

RefSeq NM_005163

UniProt P31749

Other data

Locus Chr. 17 p13.1

p87^PIKAP is a regulatory subunit of the type IB Phosphoinositide 3-Kinase p110γ. Its also referred to as p84 and p87.

Functions

References

1.Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.

Kurig B, Shymanets A, Bohnacker T, Prajwal, Brock C, Ahmadian MR, Schaefer M, Gohla A, Harteneck C, Wymann MP, Jeanclos E, Nürnberg B.

Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20312-7. Epub 2009 Nov 11.

2. Characterization of P87Pikap, a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B

Philipp Voigt, Martin B. Dorner, and Michael Schaefer

J. Biol. Chem., Vol. 281, Issue 15, 9977-9986, April 14, 2006

The context of the function of p87.

Categories:
Genes on chromosome 17
Biology stubs

Phosphoinositide-3-kinase adapter protein of 87 kDa
Identifiers
Symbol	p87^PIKAP
Alt. symbols	p84,PIK3R6
Entrez	146850
HUGO	27101
OMIM	164730
RefSeq	NM_005163
UniProt	P31749
Other data
Locus	Chr. 17 p13.1

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Class I PI 3-kinases — are a subgroup of the enzyme family, phosphoinositide 3 kinase that possess a common protein domain structure, substrate specificity, and method of activation. Class I PI 3 kinases are further divided into two subclasses, class IA PI 3 kinases… … Wikipedia
PIK3CG — Phosphoinositide 3 kinase, catalytic, gamma polypeptide PDB rendering based on 17eu … Wikipedia

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