TRAMP complex

TRAMP complex

The TRAMP complex (Trf4/Air2/Mtr4p Polyadenylation complex) is a multi-protein complex consisting of the RNA helicase "Mtr4", a poly(A) polymerase (PAP) (either "Trf4" or "Trf5") and a zinc knuckle protein (either "Air1" or "Air2"). The TRAMP complex interacts with the exosome complex in the nucleus of eukaryotic cells and is involved in the 3' end processing of ribosomal RNA and snoRNAs. [cite journal
author=LaCava "et al."
title=RNA degradation by the exosome is promoted by a nuclear polyadenylation complex
journal=Cell
year=2005
volume=121
pages=713–24
pmid=15935758
doi=10.1016/j.cell.2005.04.029
]

References


Wikimedia Foundation. 2010.

Игры ⚽ Нужен реферат?

Look at other dictionaries:

  • Exosome complex — The exosome complex (or PM/Scl complex, often just called the exosome) is a multi protein complex, capable of degrading various types of RNAs. Exosome complexes can be found in both eukaryotic cells and archaea, while in bacteria a simpler… …   Wikipedia

  • Polyadenylation — Typical structure of a mature eukaryotic mRNA Polyadenylation is the addition of a poly(A) tail to an RNA molecule. The poly(A) tail consists of multiple adenosine monophosphates; in other words, it is a stretch of RNA that has only adenine bases …   Wikipedia

  • literature — /lit euhr euh cheuhr, choor , li treuh /, n. 1. writings in which expression and form, in connection with ideas of permanent and universal interest, are characteristic or essential features, as poetry, novels, history, biography, and essays. 2.… …   Universalium

  • ship — shipless, adj. shiplessly, adv. /ship/, n., v., shipped, shipping. n. 1. a vessel, esp. a large oceangoing one propelled by sails or engines. 2. Naut. a. a sailing vessel square rigged on all of three or more masts, having jibs, staysails, and a… …   Universalium

  • Charlie Chaplin — For other people named Charles Chaplin, see Charles Chaplin (disambiguation). Charlie Chaplin …   Wikipedia

  • Ant — For other uses, see Ant (disambiguation). Ants Temporal range: 130–0 Ma …   Wikipedia

  • motion picture, history of the — Introduction       history of the medium from the 19th century to the present. Early years, 1830–1910 Origins       The illusion of motion pictures is based on the optical phenomena known as persistence of vision and the phi phenomenon. The first …   Universalium

  • History of film — This article is about the history of cinema. For other uses, see History of photography. Years in film 1870s 1880s 1890s …   Wikipedia

  • John F. Kennedy assassination conspiracy theories — President Kennedy, Jackie Kennedy, Nellie Connally and Governor John Connally, shortly before the assassination. There has long been suspicion of a government cover up of information about the assassination of John F. Kennedy on November 22, 1963 …   Wikipedia

  • Robert A. Heinlein — Heinlein signing autographs at the 1976 Worldcon Born July 7, 1907(1907 07 07) Butler, Missouri, United States Died …   Wikipedia

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”