Scyllo-inositol

Scyllo-inositol

Scyllo-Inositol is a cyclohexanehexol stereoisomerAlso known as: Scyllitol, Cocositol, Quercinitol, 1,3,5/2,4,6-Hexahydroxycyclohexane Molecular Formula: C6H12O6 Molecular Weight: 180.16 Melting Point: 348.5-350°C Appearance: White Crystalline Solid

Scyllitol is a naturally occurring plant sugar alcohol found most abundantly in the coconut palm.

JoAnne McLaurin, Peter St. George-Hyslop, and colleagues at the University of Toronto have found scyllo-inositol (also called "scyllitol") when fed to transgenic mice that exhibit a memory disease very similar to human Alzheimer's disease, can block the accumulation of soluble amyloid-beta (Aβ) plaques in the brain. The research team found that scyllitol reversed memory deficits in the mice, reduce the amount of Aβ plaque in the brains of the mice, and reversed other symptoms associated with the presence of Aβ in the brain.

ources

*http://www.alzforum.org/new/detail.asp?id=1414
*http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=16767098
* [http://www.ars-grin.gov/cgi-bin/duke/chemical.pl?SCYLLITOL Dr. Duke's Phytochemical and Ethnobotanical Databases]


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  • scyllo-Inositol — IUPAC name (1R,2R,3R,4R,5R,6R) Cyclohexane 1,2,3,4,5,6 hexaol …   Wikipedia

  • Guanidinodeoxy-scyllo-inositol-4-phosphatase — In enzymology, a guanidinodeoxy scyllo inositol 4 phosphatase (EC number|3.1.3.40) is an enzyme that catalyzes the chemical reaction:1 guanidino 1 deoxy scyllo inositol 4 phosphate + H2O ightleftharpoons 1 guanidino 1 deoxy scyllo inositol +… …   Wikipedia

  • 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase — In enzymology, a 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol transaminase (EC number|2.6.1.56) is an enzyme that catalyzes the chemical reaction:1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol + pyruvate ightleftharpoons 1D 1 guanidino… …   Wikipedia

  • Glutamine-scyllo-inositol transaminase — In enzymology, a glutamine scyllo inositol transaminase (EC number|2.6.1.50) is an enzyme that catalyzes the chemical reaction:L glutamine + 2,4,6/3,5 pentahydroxycyclohexanone ightleftharpoons 2 oxoglutaramate + 1 amino 1 deoxy scyllo… …   Wikipedia

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  • Scyllo-inosamine 4-kinase — In enzymology, a scyllo inosamine 4 kinase (EC number|2.7.1.65) is an enzyme that catalyzes the chemical reaction:ATP + 1 amino 1 deoxy scyllo inositol ightleftharpoons ADP + 1 amino 1 deoxy scyllo inositol 4 phosphateThus, the two substrates of… …   Wikipedia

  • Scyllo-inosamine-4-phosphate amidinotransferase — In enzymology, a scyllo inosamine 4 phosphate amidinotransferase (EC number|2.1.4.2) is an enzyme that catalyzes the chemical reaction:L arginine + 1 amino 1 deoxy scyllo inositol 4 phosphate ightleftharpoons L ornithine + 1 guanidino 1 deoxy… …   Wikipedia

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  • Inositol — Estructura del inositol. Inositol o ciclohexan 1,2,3,4,5,6 hexol es un compuesto orgánico de fórmula a C6H12O6 o ( CHOH )6, un poliol del ciclohexano. Existen nueve posibles estereoisómeros, de los cuales el más común y más extendido en la… …   Wikipedia Español

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