Isoxazole

Isoxazole

Chembox new
ImageFile=Isoxazole_chemical_structure.pngImageSize=
IUPACName=isoxazole
OtherNames=
Section1= Chembox Identifiers
CASNo=288-14-2
PubChem=9254
SMILES=C1=CON=C1
Section2= Chembox Properties
Formula=C3H3NO
MolarMass=69.06202
Appearance=
Density=1.075 g/ml
MeltingPt=
BoilingPt=95 °C
Solubility=
Section3= Chembox Hazards
MainHazards=
FlashPt=
Autoignition=

Isoxazole is an azole with an oxygen atom next to the nitrogen.

Isoxazoles are found in some natural products, such as ibotenic acid. Isoxazoles also form the basis for a number of drugs, including the COX-2 inhibitor valdecoxib (Bextra). Furoxan is a nitric oxide donor.

See also

* Oxazole, an analog with the nitrogen atom in position 3.
* Pyrrole, an analog without the oxygen atom.
* Furan, an analog without the nitrogen atom.
* Simple aromatic rings

External links

* [http://www.organic-chemistry.org/synthesis/heterocycles/isoxazoles.shtm Synthesis of isoxazoles (overview of recent methods)]


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