Saccharomyces kluyveri

Taxobox
name = ""
regnum = Fungi
phylum = Ascomycota
classis = Saccharomycetes
subclassis = Saccharomycetidae
ordo = Saccharomycetales
familia = Saccharomycetaceae
genus = "Saccharomyces"
species = "S. kluyveri"
binomial = "Saccharomyces kluyveri"
binomial_authority = Phaff, M.W. Mill. & Shifrine, (1956)

Saccharomyces kluyveri is a plant pathogen.

Habitat

"S. kluyveri"'s habitat has not been as extensively characterized as that of yeast species such as "S. cerevisiae" or "Candida" albicans; only about 30 isolates have been described. However, the species appears to be wide spread in the environment. It has been isolated from "Drosophila" species in North America, soil in Europe, and various tree species in India and North America. Little data has been published on S. kluyveri's habitat since it was first described in 1956, but there is a report of "S. kluyveri" being isolated from the tissues of an HIV infected patient. [http://genome.wustl.edu/genome.cgi?GENOME=Saccharomyces%20kluyveri S.kluyveri Genome sequencing project] ]

Biology

"Saccharomyces kluyveri" is a budding yeast related to "Saccharomyces cerevisiae", or baker's yeast, the model organism intensively used in biochemistry, genetics and cell biology. "S. cerevisiae" and "S. kluyveri" have several fundamental differences that warrant genomic comparisons. First, like most cell types, "S. kluyveri" resorts to fermentation (degrading sugars in the absence of oxygen) only when oxygen is limiting. "S. cerevisiae", on the other hand, prefers to carry out fermentation even in the presence of oxygen. This means that "S. kluyveri" makes a more efficient use of glucose for energy production. Therefore, "S. kluyveri" provides a contrasting model to one of the most unique features of S. cerevisiae. Second, "S. kluyveri" has a simpler genome organization than "S. cerevisiae": it appears to have become a species before the whole genome duplication that occurred in the Saccharomyces lineage. As a result, its genome is smaller (about 9.5 million base pairs) than that of "S. cerevisiae" with fewer duplicated genes. Additionally, "S. kluyveri" is becoming more widely used as a model organism and for industrial applications, such as the production of proteins, since its biomass yield is greater than that of "S. cerevisiae" due to more efficient use of glucose.

equencing information

The "S. kluyveri" genome was originally sequenced in 2002 to approximately 3.5X whole genome shotgun (WGS) coverage in collaboration with Mark Johnston in the Department of Genetics. We have now completed an additional 4X coverage of the genome including WGS and 25X clone coverage of fosmid end sequence templates, yielding a total of 7.5X genome coverage. Manual and automated finishing are ongoing, with 10,000 reactions planned. The National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), provided the funding for the genome sequence.

External links

* [http://www.speciesfungorum.org/Names/Names.asp Index Fungorum]
* [http://nt.ars-grin.gov/fungaldatabases USDA ARS Fungal Database]

References