NIM811

NIM811
NIM811
Identifiers
CAS number 143205-42-9 YesY
PubChem 6473876
UNII 96262S4I14 YesY
ChEMBL CHEMBL1688529 N
Jmol-3D images Image 1
Properties
Molecular formula C62H111N11O12
Molar mass 1202.61
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

NIM811 is a mitochondrial permeability transition inhibitor. Also known as N-methyl-4-isoleucine cyclosporin, it is a four-substituted cyclosporine that does not bind to cyclophilin A and therefore lacks immunosuppressive activity. Rather, NIM811 binds and inhibits cyclophilin.



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Look at other dictionaries:

  • Mitochondrial permeability transition — Mitochondrial permeability transition, or MPT, is an increase in the permeability of the mitochondrial membranes to molecules of less than 1500 Daltons in molecular weight. MPT results from opening of mitochondrial permeability transition pores,… …   Wikipedia

  • Mitochondrial permeability transition pore — The Mitochondrial Permeability Transition, or MPT, is defined as an increase in the permeability of the mitochondrial membranes to molecules of less than 1500 Daltons in molecular weight. MPT results from the opening of a mitochondrial… …   Wikipedia

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