Facial nerve paralysis

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ICD9 = ICD9|351
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eMedicineSubj = plastic
eMedicineTopic = 522
MeshID = D005158

Facial nerve paralysis is a common problem that involves the paralysis of any structures innervated by the facial nerve. The pathway of the facial nerve is long and relatively convoluted, and so there are a number of causes that may result in facial nerve paralysis. The most common is Bell's palsy, an idiopathic disease that may only be diagnosed by exclusion.

A thorough medical history and physical examination are the first steps in making a diagnosis.

During the physical examination, a distinction must first be made between paralysis and paresis (incomplete paralysis). Not surprisingly, paralysis is far more serious and requires immediate treatment. It must also be determined whether the forehead is involved in the motor defect or not. This is usually accomplished by assessing how well a patient can raise her eyebrows. The question is an important one because it helps determine if the lesion is in the upper motor neuron component of the facial nerve, or in its lower motor neuron component.

Laboratory investigations include an audiogram, nerve conduction studies (ENoG), computed tomography (CT) or magnetic resonance imaging (MRI).

Causes

Bell's palsy

Bell's palsy is the most common cause of acute facial nerve paralysis (>80%). Previously considered idiopathic, it has been recently linked to herpes simplex infection. Another more severe form of facial palsy, called Ramsay-Hunt syndrome, is linked to herpes zoster infection of the facial nerve. Other, less common, etiologies are Lyme disease) polio, TB..

Bell's palsy is an exclusion diagnosis. Some factors that tend to rule out Bell's palsy include:
# Recurrent paralysis
# Slowly progressive paralysis (The onset of Bell's palsy is very sudden)
# Twitching
# Associated symptoms (either cochlear or neurologic)Bell's palsy is believed in the most recent studies to be due to herpes virus. Other proposed etiologies include vascular problems in the inner ear. Treatment include steroids and antivirals.

Trauma

Physical trauma, especially fractures of the temporal bone, may also cause acute facial nerve paralysis. Understandably, the likelihood of facial paralysis after trauma depends on the location of the trauma. Most commonly, facial paralysis follows temporal bone fractures, though the likelihood depends on the type of fracture.

"Transverse fractures" in the horizontal plane present the highest likelihood of facial paralysis (40-50%). Patients may also present with hemotympanum (blood behind the tympanic membrane), sensory deafness, and vertigo – the latter two symptoms due to damage to vestibulocochlear nerve (cranial nerve VIII) and the inner ear. "Longitudinal fracture" in the vertical plane present a lower likelihood of paralysis (20%). Patients may present with hematorrhea (blood coming out of the external auditory meatus), tympanic membrane tear, fracture of external auditory canal, and conductive hearing loss.

Traumatic injuries can be assessed by computed tomography (CT) and nerve conduction studies (ENoG). In patients with mild injury, management is the same as with Bell's palsy – protect the eyes and wait. In patients with severe injury, progress is followed with nerve conduction studies. If nerve conduction studies show a large (>90%) change in nerve conduction, the nerve should be decompressed. The facial paralysis can follow immediately the trauma due to direct damage to the facial nerve, in such cases a surgical treatment may be attempted. In other cases the facial paralysis can occur a long time after the trauma due to oedema and inflammation. In those cases steroids can be a good help.

Tumours

A tumour compressing the facial nerve anywhere along its complex pathway can result in facial paralysis. Common culprits are facial neuromas, congenital cholesteatomas, hemangiomas, acoustic neuromas, parotid gland neoplasms, or metastases of other tumours.

Patients with facial nerve paralysis resulting from tumours usually present with a progressive, twitching paralysis, other neurological signs, or a recurrent Bell's palsy-type presentation.The latter should always be suspicious, as Bell's palsy should not recur. A chronically discharging ear must be treated as a cholesteatoma until proven otherwise; hence, there must be immediate surgical exploration.

Computed tomography (CT) or magnetic resonance (MR) imaging should be used to identify the location of the tumour, and it should be managed accordingly.

"Herpes zoster oticus"

Herpes zoster oticus is essentially a herpes zoster infection that affects cranial nerves VII (facial nerve) and VIII (vestibulocochlear nerve).Patients present with facial paralysis, ear pain, vesicles, sensorineural hearing loss, and vertigo.Management includes antivirals and oral steroids.

Acute and chronic "otitis media"

"Otitis media" is an infection in the middle ear, which can spread to the facial nerve and inflame it, causing compression of the nerve in its canal.
Antibiotics are used to control the "otitis media", and other options include a wide myringotomy (an incision in the tympanic membrane) or decompression if the patient does not improve

Chronic "otitis media" usually presents in an ear with chronic discharge (otorrhea), or hearing loss, with or without ear pain (otalgia). Once suspected, there should be immediate surgical exploration to determine if a cholesteatoma has formed and must be removed.

Neurosarcoidosis

Facial nerve paralysis, sometimes bilateral, is a common manifestation of neurosarcoidosis (sarcoidosis of the nervous system), itself a rare condition.

Moebius syndrome

Moebius syndrome is a bilateral facial paralysis resulting from the underdevelopment of the VII cranial nerve (facial nerve), which is present at birth. The VI cranial nerve, which controls lateral eye movement, is also affected, so people with Moebius syndrome cannot form facial expression or move their eyes from side to side. Moebius syndrome is extremely rare, and its cause or causes are not known.

References

* [http://www.med.uwo.ca/UME/Diane/Year2Postings2004-2005/Trimester%202/CNS/AcuteFacialParalysisPowerpointDrParnes.ppt Acute facial nerve paralysis] - Powerpoint slides from a lecture presented to second year medical school students at the [http://www.uwo.ca/ University of Western Ontario] by Dr. Lorne Parnes on 19 November 2004. These notes are licensed under the FDL.
* [http://www.med.uwo.ca/UME/Diane/Year2Postings2004-2005/Trimester%202/CNS/AcuteFacialNerveParalysisDrParnes.pdf Acute facial nerve paralysis] - Notes from a lecture presented to second year medical school students at the [http://www.uwo.ca/ University of Western Ontario] by Dr. Lorne Parnes on 19 November 2004. These notes are licensed under the FDL.